Vanguard Portfolio Management LLC filed Amendment No. 2 to its Schedule 13G with the SEC on October 30, 2026, disclosing beneficial ownership of 1,741,113 shares of Inspire Medical Systems Inc common stock as of September 30, 2026.

Key Highlights

  • Aggregate beneficial ownership: Vanguard Portfolio Management reported 1,741,113 shares of Inspire Medical Systems Inc common stock beneficially owned.
  • Percent of class: The reported holdings represent 6.02% of the class of securities.
  • Sole voting power: Vanguard Portfolio Management holds sole voting power over 36,509 shares.
  • Sole dispositive power: The filing reports sole dispositive power over all 1,741,113 shares, with no shared dispositive power.
  • Event date: The date of the event requiring this filing is September 30, 2026.
  • Affiliates included: The filing covers securities beneficially owned by Vanguard Portfolio Management LLC and its affiliates Vanguard Fiduciary Trust Company and Vanguard Global Advisers, LLC.

Vanguard Portfolio Management's Reported Stake in Inspire Medical Systems

According to the filing, Vanguard Portfolio Management, organized in Pennsylvania and operating as an investment adviser, submitted Amendment No. 2 to its Schedule 13G concerning its holdings in Inspire Medical Systems Inc (NYSE:INSP), whose principal executive offices are located at 5500 Wayzata Blvd, Suite 1600, Minneapolis, MN 55416. The event triggering this amended filing occurred on September 30, 2026.

The filing discloses that Vanguard Portfolio Management beneficially owns 1,741,113 shares of Inspire Medical Systems common stock (CUSIP 457730109), representing 6.02% of the class. Of those shares, the registrant reports sole voting power over 36,509 shares and sole dispositive power over the full 1,741,113 shares. Shared voting power and shared dispositive power are each reported as zero.

The filing notes, in accordance with SEC Release No. 34-39538 (January 12, 1998), that the Schedule 13G reflects securities beneficially owned or deemed to be beneficially owned by Vanguard Portfolio Management LLC and its affiliates Vanguard Fiduciary Trust Company and Vanguard Global Advisers, LLC. It includes securities held by Vanguard funds or sleeves thereof over which Vanguard Portfolio Management LLC exercises dispositive power, as well as securities held by clients over which the named affiliates exercise dispositive and/or voting power. The filing further states that it "does not include securities, if any, beneficially owned by other subsidiaries or affiliates of Vanguard Portfolio Management LLC" whose ownership is disaggregated in accordance with that release. The document was signed by My Trieu-Gatt, identified as Authorized Signatory and Head of Global Fund Administration, on October 30, 2026. The filing also states that no single other person's interest in the reported securities exceeds 5%.

What Was Disclosed

Vanguard Portfolio Management filed Amendment No. 2 to Schedule 13G, reporting beneficial ownership of 1,741,113 shares, or 6.02%, of Inspire Medical Systems Inc common stock as of September 30, 2026, with sole dispositive power over all reported shares and sole voting power over 36,509 shares.