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Apellis price target lowered to $20 from $28 at Scotiabank
Fri 09 May 25, 02:35 PMApellis Pharmaceuticals downgraded by Raymond James due to ’added uncertainty’
Fri 09 May 25, 01:18 PMIs Apellis Pharmaceuticals, Inc. (APLS) The Best Stock That Will Bounce Back?
Fri 09 May 25, 12:46 PMApellis' Q1 Earnings and Revenues Miss Estimates, Stock Down
Thu 08 May 25, 02:43 PMQ1 2025 Apellis Pharmaceuticals Inc Earnings Call
Thu 08 May 25, 04:45 AMWhy Apellis Pharmaceuticals Wilted on Wednesday
Wed 07 May 25, 10:09 PMApellis Pharmaceuticals (APLS) Reports Q1 Earnings: What Key Metrics Have to Say
Wed 07 May 25, 01:30 PMApellis Pharmaceuticals, Inc. (APLS) Reports Q1 Loss, Lags Revenue Estimates
Wed 07 May 25, 12:10 PMApellis Pharmaceuticals Reports First Quarter 2025 Financial Results
Wed 07 May 25, 11:00 AM| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | 24.11M | -196.71600M | -526.49600M | -651.50300M | -746.00200M |
| Minority interest | - | - | - | - | - |
| Net income | 22.39M | -197.87800M | -528.62800M | -652.17200M | -746.35400M |
| Selling general administrative | 550.26M | 417.75M | 500.81M | 277.16M | 176.77M |
| Selling and marketing expenses | - | 83.30M | 1.70M | - | - |
| Gross profit | 901.55M | 663.64M | 338.08M | 69.79M | 61.36M |
| Reconciled depreciation | 1.56M | 1.80M | 1.70M | 1.49M | 1.49M |
| Ebit | 68.44M | -156.32500M | -496.91500M | -594.61300M | -536.27700M |
| Ebitda | 70.00M | -154.52800M | -495.21100M | -584.50000M | -533.00500M |
| Depreciation and amortization | 1.56M | 1.80M | 1.70M | 10.11M | 3.27M |
| Non operating income net other | - | - | - | - | - |
| Operating income | 55.43M | -164.97900M | -517.12100M | -594.61300M | -536.27700M |
| Other operating expenses | 948.36M | 946.35M | 913.71M | 670.03M | 602.84M |
| Interest expense | 44.33M | 40.39M | 29.58M | 32.63M | 13.24M |
| Tax provision | 1.72M | 1.16M | 2.13M | 0.67M | 0.35M |
| Interest income | 13.14M | 12.77M | 20.93M | 8.91M | 0.42M |
| Net interest income | -31.18400M | -27.61800M | -8.64800M | -23.71200M | -12.82300M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | 1.72M | 1.16M | 2.13M | 0.67M | 0.35M |
| Total revenue | 1003.78M | 781.37M | 396.59M | 75.42M | 66.56M |
| Total operating expenses | 846.12M | 828.62M | 855.20M | 664.40M | 597.64M |
| Cost of revenue | 102.24M | 117.72M | 58.51M | 5.64M | 5.20M |
| Total other income expense net | -31.31700M | -31.73700M | -9.37500M | -56.89000M | -209.72500M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | 22.39M | -197.87800M | -528.62800M | -652.17200M | -746.35400M |
| Net income applicable to common shares | - | - | - | -652.17200M | -746.35400M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 1075.26M | 885.05M | 788.73M | 760.22M | 881.76M |
| Intangible assets | - | - | - | - | - |
| Earning assets | - | - | - | - | - |
| Other current assets | 38.30M | 18.61M | 61.23M | 36.66M | 70.68M |
| Total liab | 705.11M | 656.51M | 594.21M | 590.35M | 683.10M |
| Total stockholder equity | 370.15M | 228.54M | 194.52M | 169.87M | 198.66M |
| Deferred long term liab | - | - | - | - | - |
| Other current liab | 166.05M | 140.18M | 203.64M | 124.64M | 7.58M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01000M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01000M |
| Retained earnings | -3012.97800M | -3035.36600M | -2837.48800M | -2308.86000M | -1656.68800M |
| Other liab | - | - | - | 315.65M | 345.15M |
| Good will | - | - | - | - | - |
| Other assets | - | - | - | 15.80M | 31.64M |
| Cash | 467.76M | 411.29M | 352.30M | 551.80M | 640.19M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 323.60M | 185.51M | 247.59M | 167.61M | 131.85M |
| Current deferred revenue | - | - | - | - | 103.24M |
| Net debt | 18.55M | 58.49M | -241.37100M | -439.08800M | -429.97200M |
| Short term debt | 100.75M | 6.75M | 6.44M | 5.62M | 4.12M |
| Short long term debt | 93.66M | - | - | - | - |
| Short long term debt total | 486.31M | 469.78M | 110.93M | 112.71M | 210.22M |
| Other stockholder equity | 3385.22M | 3267.20M | 3035.54M | 2479.60M | 1857.43M |
| Property plant equipment | - | - | - | 24.89M | 26.08M |
| Total current assets | 1014.84M | 788.95M | 766.33M | 719.52M | 824.05M |
| Long term investments | - | - | - | - | - |
| Net tangible assets | - | - | - | 169.87M | 198.66M |
| Short term investments | - | 4.85M | 4.35M | 0.00000M | 60.36M |
| Net receivables | 366.22M | 271.72M | 206.44M | 7.73M | 10.10M |
| Long term debt | 361.66M | 452.83M | 93.03M | 92.74M | 189.02M |
| Inventory | 142.56M | 82.48M | 146.36M | 85.71M | 16.29M |
| Accounts payable | 56.80M | 38.57M | 37.52M | 37.34M | 16.91M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | -2.10300M | -3.30800M | -3.54200M | -0.87500M | -2.09000M |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | - | - | - | - |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | - | - | - | - |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 40.51M | 77.06M | 1.31M | 15.80M | 31.64M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 60.42M | 96.10M | 22.40M | 40.69M | 57.72M |
| Capital lease obligations | 19.03M | 16.95M | 17.89M | 19.98M | 21.20M |
| Long term debt total | - | - | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | -0.40300M | -0.67400M | 59.89M | 248.72M |
| Change to liabilities | - | - | - | 18.69M | 10.49M |
| Total cashflows from investing activities | -0.31300M | -0.40300M | -0.67400M | 59.89M | 247.62M |
| Net borrowings | 0.00000M | 365.45M | 0.00000M | - | - |
| Total cash from financing activities | 8.88M | 149.24M | 394.50M | 365.66M | 392.24M |
| Change to operating activities | - | - | - | 32.63M | -77.58900M |
| Net income | 22.39M | -197.87800M | -528.62800M | -652.17200M | -746.35400M |
| Change in cash | 55.15M | 60.31M | -200.77500M | -88.68100M | 74.71M |
| Begin period cash flow | 412.61M | 352.30M | 553.07M | 641.75M | 567.04M |
| End period cash flow | 467.76M | 412.61M | 352.30M | 553.07M | 641.75M |
| Total cash from operating activities | 45.33M | -87.86600M | -594.73500M | -513.74500M | -563.12600M |
| Issuance of capital stock | 0.00000M | 0.00000M | 384.39M | 380.12M | 380.36M |
| Depreciation | 1.56M | 1.80M | 1.70M | 1.49M | 1.49M |
| Other cashflows from investing activities | -0.31300M | - | 0.10M | - | - |
| Dividends paid | - | - | - | - | - |
| Change to inventory | -15.26700M | -10.75500M | -60.64700M | -69.39700M | -16.31700M |
| Change to account receivables | -101.27900M | -58.48400M | -198.71500M | 2.38M | -10.10300M |
| Sale purchase of stock | - | 4.51M | -11.04000M | 4.24M | 2.97M |
| Other cashflows from financing activities | -0.01100M | -235.04100M | 10.11M | -18.69900M | 8.90M |
| Change to netincome | - | - | - | 152.11M | 274.29M |
| Capital expenditures | 0.31M | 0.40M | 0.77M | 1.52M | 1.10M |
| Change receivables | - | - | - | - | - |
| Cash flows other operating | - | - | - | - | - |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | - | - | - | - | - |
| Change in working capital | -85.11800M | -18.35700M | -200.16900M | -15.69800M | -93.52200M |
| Stock based compensation | 104.00M | 114.13M | 105.94M | 91.08M | 70.67M |
| Other non cash items | 108.06M | 12.44M | 26.41M | 61.55M | 6.33M |
| Free cash flow | 45.01M | -88.26900M | -595.50800M | -515.26900M | -564.22900M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to Revenue (x) | Enterprise Value to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| APLS Apellis Pharmaceuticals Inc |
- -% | - | 227.44 | 46.30 | 5.21 | 14.14 | 5.22 | 74.88 |
| NVO Novo Nordisk A/S |
-0.79 1.81% | 42.96 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
-0.6937 1.57% | 43.50 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
5.09 1.15% | 446.83 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
6.72 1.07% | 635.45 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, focal segmental glomerulosclerosis, and delayed graft function; and APL-3007, a small interfering RNA, or siRNA for the treatment of GA. In addition, it conducts preclinical studies for APL-9099, a treatment targeting the neonatal Fc receptor, or FcRn, which has the potential to be a first-in-class gene editing treatment for future target indications with one-time dosing; and developing other programs with its proprietary in-house capabilities and under its Beam collaboration. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics, Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is headquartered in Waltham, Massachusetts.
100 Fifth Avenue, Waltham, MA, United States, 02451
| Name | Title | Year Born |
|---|---|---|
| Dr. Cedric Francois M.D., Ph.D. | Co-Founder, Pres, CEO & Director | 1972 |
| Dr. Pascal Deschatelets Ph.D. | Co-Founder & Chief Scientific Officer | 1970 |
| Dr. Federico Grossi M.D., Ph.D. | Co-Founder & Chief Medical Officer | 1974 |
| Mr. Alec Machiels J.D., MBA | Co-Founder & Director | 1973 |
| Mr. Timothy E. Sullivan | CFO & Treasurer | 1971 |
| Mr. Adam J. Townsend | Chief Commercial Officer | 1977 |
| Ms. Nur Nicholson | Chief Technical Operations Officer | NA |
| Mr. James G. Chopas CPA | VP, Corp. Controller & Chief Accounting Officer | 1966 |
| Ms. Meredith Kaya | Sr. VP, Investor Relations & Strategic Fin. | NA |
| Mr. David O. Watson Esq., J.D. | Gen. Counsel | 1973 |
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