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Biomea Fusion, Inc., a clinical-stage diabetes and obesity medicines company, focuses on the discovery and development of oral covalent small molecule drugs to treat patients with metabolic diseases in the United States. It's lead product candidate icovamenib, an orally bioavailable, potent, and covalent inhibitor of menin, a ubiquitously expressed scaffold protein that functions in histone modification and epigenetic gene regulation to impact multiple cellular processes including cell cycle control, apoptosis, and DNA damage repair. Biomea Fusion, Inc. was incorporated in 2017 and is headquartered in San Carlos, California.
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Biomea Fusion Inc is a clinical-stage biopharmaceutical company developing targeted covalent small-molecule therapies for oncology. Major long-term growth drivers include clinical trial progress, successful regulatory outcomes, and partnerships or licensing that could support commercialization, and the company appears positioned to benefit if its discovery chemistry translates to differentiated drug candidates. Investors may find the company attractive because proof-of-concept in one or more programs could materially increase value given limited current revenues.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -61.80M | -138.43M | -117.25M | -81.83M | -41.57M |
| Net income | -61.80M | -138.43M | -117.25M | -80.02M | -41.22M |
| Selling general administrative | 19.33M | 25.98M | 23.59M | 20.92M | 13.67M |
| Selling and marketing expenses | - | - | 4.20M | - | - |
| Gross profit | -1.41M | -1.75M | -4.20M | - | - |
| Reconciled depreciation | 1.41M | 1.75M | 1.51M | 0.69M | 0.25M |
| Ebit | -81.31M | -144.07M | -126.14M | -84.33M | -41.92M |
| Ebitda | -79.90M | -142.32M | -124.62M | -83.63M | -41.67M |
| Depreciation and amortization | 1.41M | 1.75M | 1.51M | 0.69M | 0.25M |
| Non operating income net other | - | - | - | 1.81M | - |
| Operating income | -81.31M | -144.07M | -126.14M | -83.63M | -41.67M |
| Other operating expenses | 81.31M | 144.07M | 126.14M | 83.63M | 41.67M |
| Interest expense | - | - | - | -1.81M | 0.10M |
| Interest income | 1.86M | 5.64M | 8.88M | 1.81M | 0.10M |
| Net interest income | 1.86M | 5.64M | 8.88M | 1.81M | 0.10M |
| Income tax expense | - | - | - | -1.81M | -0.35M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 79.90M | 144.07M | 126.14M | 83.63M | 41.67M |
| Cost of revenue | 1.41M | 1.75M | 4.20M | - | - |
| Total other income expense net | 19.51M | 5.64M | 8.88M | 1.81M | 0.10M |
| Net income from continuing ops | -61.80M | -138.43M | -117.25M | -81.83M | -41.57M |
| Net income applicable to common shares | - | - | - | -81.83M | -41.57M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 58.57M | 79.94M | 199.93M | 129.31M | 185.71M |
| Other current assets | 2.24M | 10.05M | 2.31M | 4.77M | 3.04M |
| Total liab | 29.02M | 28.36M | 30.69M | 20.77M | 6.92M |
| Total stockholder equity | 29.55M | 51.57M | 169.24M | 108.54M | 178.78M |
| Other current liab | 6.41M | 6.66M | 13.54M | 11.66M | 0.48M |
| Common stock | 0.01M | 0.00M | 0.00M | 0.00M | 0.00M |
| Capital stock | 0.01M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -449.05M | -387.25M | -248.82M | -131.57M | -49.74M |
| Other assets | - | - | 0.00M | - | 1.58M |
| Cash | 55.81M | 58.28M | 176.87M | 113.40M | 175.74M |
| Total current liabilities | 11.10M | 21.67M | 22.86M | 19.10M | 4.64M |
| Current deferred revenue | - | - | - | - | 2.26M |
| Net debt | -54.22M | -49.51M | -166.57M | -111.11M | -172.89M |
| Short term debt | 1.46M | 2.08M | 2.47M | 0.62M | 0.56M |
| Short long term debt total | 1.59M | 8.77M | 10.30M | 2.29M | 2.85M |
| Other stockholder equity | 478.59M | 438.82M | 418.06M | 240.11M | 42.83M |
| Property plant equipment | - | - | - | 5.84M | 5.69M |
| Total current assets | 58.05M | 68.33M | 179.18M | 117.82M | 176.56M |
| Long term investments | - | - | 0.00M | 0.00M | 1.88M |
| Net tangible assets | - | - | - | 108.54M | 178.78M |
| Short term investments | - | - | 0.00M | 1.15M | 27.78M |
| Accounts payable | 3.23M | 12.93M | 6.85M | 6.83M | 1.33M |
| Accumulated other comprehensive income | - | - | - | -0.00M | -0.01M |
| Common stock total equity | - | - | - | 0.00M | 0.00M |
| Retained earnings total equity | - | - | - | -131.57M | -49.74M |
| Non currrent assets other | 0.37M | 0.99M | 2.46M | 3.50M | 1.58M |
| Non current assets total | 0.52M | 11.61M | 20.75M | 11.49M | 9.14M |
| Capital lease obligations | 1.59M | 8.77M | 10.30M | 2.29M | 2.85M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 0.00M | -0.36M | -2.22M | 28.37M | -30.18M |
| Change to liabilities | - | - | - | 11.87M | 0.64M |
| Total cashflows from investing activities | - | -0.36M | -2.22M | 27.34M | -33.35M |
| Net borrowings | - | - | 0.00M | - | -0.04M |
| Total cash from financing activities | 67.90M | 1.67M | 163.80M | 1.24M | 153.19M |
| Change to operating activities | - | - | - | - | -2.21M |
| Net income | -61.80M | -138.43M | -117.25M | -81.83M | -41.57M |
| Change in cash | -2.47M | -118.59M | 64.99M | -33.84M | 84.39M |
| Begin period cash flow | 58.65M | 177.24M | 112.25M | 146.09M | 61.70M |
| End period cash flow | 56.18M | 58.65M | 177.24M | 112.25M | 146.09M |
| Total cash from operating activities | -70.37M | -119.89M | -96.59M | -62.42M | -35.44M |
| Issuance of capital stock | 67.75M | 0.00M | 161.80M | 0.00M | 152.75M |
| Depreciation | 1.41M | 1.75M | 1.51M | 0.69M | 0.25M |
| Other cashflows from investing activities | - | -0.36M | - | - | - |
| Sale purchase of stock | - | - | - | 1.24M | 153.22M |
| Other cashflows from financing activities | - | 1.67M | 2.00M | 27.34M | 0.43M |
| Change to netincome | - | - | - | 10.34M | 7.45M |
| Capital expenditures | 0.00M | 0.36M | 3.37M | 1.03M | 3.17M |
| Cash flows other operating | - | - | - | -3.63M | -3.62M |
| Cash and cash equivalents changes | - | - | - | -33.84M | 84.39M |
| Change in working capital | -3.70M | -5.15M | 2.33M | 7.67M | -1.57M |
| Stock based compensation | 9.52M | 19.09M | 14.13M | 10.34M | 6.23M |
| Other non cash items | -15.80M | 4.59M | 2.69M | 0.71M | 0.70M |
| Free cash flow | -70.37M | -120.26M | -99.96M | -63.45M | -38.61M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| BMEA Biomea Fusion Inc |
0.00 0.54% |
0.65 | - | - | - | 5.01 | -3.75 |
| NVO Novo Nordisk A/S |
-0.28 0.72% |
38.39 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
13.80 2.65% |
534.83 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.69 0.21% |
817.78 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
790.15 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Biomea Fusion, Inc., a clinical-stage diabetes and obesity medicines company, focuses on the discovery and development of oral covalent small molecule drugs to treat patients with metabolic diseases in the United States. It's lead product candidate icovamenib, an orally bioavailable, potent, and covalent inhibitor of menin, a ubiquitously expressed scaffold protein that functions in histone modification and epigenetic gene regulation to impact multiple cellular processes including cell cycle control, apoptosis, and DNA damage repair. Biomea Fusion, Inc. was incorporated in 2017 and is headquartered in San Carlos, California.
| Name | Title | Year Born |
|---|---|---|
| Mr. Thomas Andrew Butler | Co-Founder, Chairman & CEO | 1981 |
| Mr. Ramses M. Erdtmann | Co-Founder, Pres, COO & Director | 1963 |
| Mr. Franco Valle | CFO & Principal Accounting Officer | 1981 |
| Mr. Heow Tan | Chief Technology & Quality Officer | 1959 |
| Ms. Naomi Cretcher | Chief People Officer | NA |
| Dr. Thorsten Kirschberg Ph.D. | Exec. VP of Chemistry | 1970 |
| Dr. Stephan Morris M.D. | Chief Medical Officer | NA |
| Mr. Ravi Upasani | Sr. VP of Intellectual Property | NA |
| Mr. Ramses M. Erdtmann | Co-Founder, President, COO & Director | 1963 |
| Dr. Thorsten Kirschberg Ph.D. | Executive Vice President of Chemistry | 1970 |
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