InflaRx is a Jena, Germany-based biopharmaceutical company founded in 2007 that develops first-in-class inhibitors of the complementFactorC5a and its receptor C5aR to treat inflammatory and autoimmune diseases. Its lead candidate is izicopan, an oral small molecule C5aR inhibitor, and it also developed vilobelimab, marketed …
Inspire Medical Systems is a Golden Valley, Minnesota-based medical technology company founded in 2007 as a spin-out from Medtronic. It develops and commercializes minimally invasive therapies for moderate to severe obstructive sleep apnea, led by the Inspire system, an implantable, closed-loop neurostimulation therapy that …
Jazz Pharmaceuticals is a Dublin-headquartered global biopharmaceutical company founded in 2003 that develops and commercializes medicines for rare and serious diseases in neuroscience and oncology. Its marketed portfolio includes Xywav for narcolepsy and idiopathic hypersomnia, Epidiolex for rare epilepsies, and oncology products such as …
Jin Medical International is a Cayman IslandsHolding Companythat operates through Chinese entities based in Changzhou, Jiangsu Province. Founded in 2006, it designs, develops, manufactures and sells manual and electric wheelchairs, wheelchair components and rehabilitation aids, including oxygen concentrators, bath aids, walking aids, micro-hyperbaric oxygen …
Madrigal Pharmaceuticals is a West Conshohocken, Pennsylvania-based commercial-stage biopharmaceutical company focused on metabolic dysfunction-associated steatohepatitis, or MASH. Its sole marketed product, Rezdiffra, is a once-daily, oral, liver-directed THR-beta agonist and was the first medication approved by the FDA and European Commission for MASH with …
Merck is a Rahway, New Jersey-based drugmaker known as MSD outside the United States and Canada. Its Pharmaceuticals segment is led by the Keytruda cancer immunotherapy and also covers vaccines, infectious disease, cardiovascular and immunology products, while its Animal Health segment sells veterinary medicines …
Neurocrine is a San Diego-based neuroscience-focused biopharmaceutical company founded in 1992. Its flagship product, Ingrezza, a VMAT2 inhibitor for tardive dyskinesia and Huntington's disease chorea, is complemented by Crenessity for congenital adrenal hyperplasia, Orilissa and Oriahnn for women's health, and the newly acquired Vykat …
Parabilis Medicines, formerly Fog Pharmaceuticals and based in Cambridge, Massachusetts, is a clinical-stage biopharmaceutical company that uses its proprietary, AI- and physics-enabled Helicon platform to engineer stabilized, cell-penetrant helical peptides targeting historically undruggable intracellular proteins, mainly in oncology. It has about 145 employees and …
Pasithea is a Miami Beach-based clinical-stage biotechnology company founded in 2020 that develops treatments for RASopathies, MAPK pathway-driven tumors and central nervous system disorders. Its lead candidate, PAS-004, is a next-generation oral macrocyclic MEK inhibitor, and the pipeline also includes PAS-003 for ALS and …
Pfizer is a New York-based global biopharmaceutical company founded in 1849 that discovers, develops and manufactures medicines and vaccines across oncology, internal medicine, vaccines, inflammation and immunology, rare disease and hospital care. Its portfolio includes Eliquis, the Prevnar family, Comirnaty, Paxlovid, Ibrance and Xtandi, …