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Provectus Biopharmaceuticals, Inc., a clinical-stage biotechnology company, engages in developing immunotherapy medicines based on halogenated xanthenes. The company's lead molecule is rose bengal sodium (RBS). Its clinical development programs include PV-10 for the treatment of stage III and IV melanoma and different types of liver cancers; PH-10 for the treatment of psoriasis and atopic dermatitis; and PV-305 for the treatment of infectious keratitis. The company is also developing oral formulations for adult solid tumor cancers, as well as refractory and relapsed pediatric, and other blood cancers comprising leukemias; PV-10 for the treatment of relapsed and refractory pediatric solid tumor cancers; and other formulations for the treatment of cutaneous canine cancers and healing of full-thickness cutaneous wounds. In addition, it develops oral and intranasal formulations for the treatment of severe acute respiratory syndrome coronavirus 2; gram-positive and gram-negative bacterial infections; oral bacterial infections; and fungal infections; as well as vertebrate development, wound healing, and tissue regrowth. The company has collaboration agreement with Bascom Palmer Eye Institute; and University of Miami. The company was formerly known as Provectus Pharmaceuticals, Inc. and changed its name to Provectus Biopharmaceuticals, Inc. in December 2013. Provectus Biopharmaceuticals, Inc. was founded in 2002 and is based in Knoxville, Tennessee.
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Provectus Biopharmaceuticals is a clinical-stage company developing an intratumoral immunotherapy based on rose bengal for treatment of solid tumors. Long-term growth drivers include positive clinical data, regulatory approvals, licensing or commercialization partnerships and expansion into additional oncology indications. The therapy may benefit patients by causing local tumor ablation with potential systemic immune responses, and investors may find exposure to a differentiated, development-stage oncology asset attractive.
Primary risks are clinical or regulatory setbacks, persistent need for external financing, lack of commercial revenue and low trading liquidity of its OTCQB listing.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -3.55M | -5.54M | -6.68M | -7.73M | -9.00M |
| Net income | -3.55M | -5.54M | -6.68M | -6.92M | -8.15M |
| Selling general administrative | 2.02M | 2.05M | 2.15M | 2.30M | 3.31M |
| Gross profit | - | - | - | - | 0.00M |
| Reconciled depreciation | 0.01M | 0.01M | 0.24M | 0.69M | 0.69M |
| Ebit | -3.39M | -4.64M | -4.93M | -6.28M | -8.03M |
| Ebitda | -3.38M | -4.56M | -4.69M | -4.78M | -6.50M |
| Non operating income net other | - | - | 0.03M | 0.02M | 0.02M |
| Operating income | -3.39M | -4.64M | -4.96M | -6.30M | -8.05M |
| Interest expense | 0.16M | 0.96M | 1.75M | 1.46M | 0.97M |
| Interest income | - | 0.00M | 0.00M | 0.02M | 0.02M |
| Net interest income | -0.16M | -0.96M | -1.74M | -1.46M | -0.97M |
| Non recurring | - | - | - | -0.68M | -0.82M |
| Income tax expense | - | - | - | - | 0.00M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 3.39M | 4.64M | 4.96M | -6.30M | 7.23M |
| Cost of revenue | - | - | - | - | 0.00M |
| Total other income expense net | 0.00M | 0.06M | -0.00M | 0.70M | 0.84M |
| Net income from continuing ops | -3.55M | -5.54M | -6.68M | -7.73M | -9.00M |
| Net income applicable to common shares | -3.55M | -5.54M | -6.68M | -6.92M | -8.15M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Total assets | 2.04M | 3.51M | 0.59M | 1.48M | 1.99M |
| Intangible assets | - | - | - | 0.23M | 0.90M |
| Other current assets | 1.41M | 2.42M | 0.32M | 0.35M | 0.37M |
| Total liab | 8.27M | 7.70M | 30.80M | 25.55M | 19.41M |
| Total stockholder equity | -6.23M | -4.19M | -30.21M | -24.07M | -17.42M |
| Other current liab | 1.51M | 2.65M | 2.09M | 0.08M | - |
| Common stock | 0.42M | 0.42M | 0.40M | 0.39M | 0.38M |
| Capital stock | 0.44M | 0.44M | 0.40M | 0.39M | 0.38M |
| Retained earnings | -249.59M | -246.03M | -240.49M | -233.82M | -226.89M |
| Other liab | - | - | - | 2.73M | - |
| Cash | 0.02M | 0.68M | 0.10M | 0.59M | 0.05M |
| Total current liabilities | 8.19M | 7.70M | 30.71M | 3.02M | 4.10M |
| Net debt | 2.05M | 1.02M | 23.57M | 19.58M | 13.88M |
| Short term debt | - | - | 16.62M | 0.50M | - |
| Short long term debt | 2.07M | 1.70M | 23.63M | 0.50M | - |
| Other stockholder equity | -0.04M | -0.03M | -0.03M | -0.02M | - |
| Property plant equipment | 0.14M | 0.07M | 0.04M | 0.06M | 0.07M |
| Total current assets | 1.90M | 3.44M | 0.42M | 1.00M | 1.02M |
| Net tangible assets | -6.25M | -4.21M | -30.21M | -24.30M | -18.32M |
| Net receivables | 0.00M | 0.01M | 0.00M | 0.06M | 0.60M |
| Long term debt | - | - | 0.04M | 13.00M | 13.93M |
| Accounts payable | 2.09M | 1.29M | 12.00M | 2.45M | 4.10M |
| Common stock total equity | - | - | 0.40M | 0.39M | 0.38M |
| Retained earnings total equity | - | - | -240.49M | -233.82M | -226.89M |
| Non currrent assets other | - | - | 0.12M | 0.19M | 0.97M |
| Non current assets total | 0.14M | 0.07M | 0.17M | 0.48M | 0.97M |
| Capital lease obligations | 0.12M | 0.05M | 0.13M | 0.21M | - |
| Long term debt total | - | - | - | 13.00M | 13.93M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | - | - | - | - | 0.00M |
| Change to liabilities | -0.18M | 2.83M | 1.82M | -0.07M | 0.65M |
| Net borrowings | 1.37M | 2.91M | 3.08M | 6.43M | 2.61M |
| Total cash from financing activities | 1.37M | 4.02M | 3.60M | 6.75M | 5.15M |
| Change to operating activities | 0.63M | 1.64M | 2.31M | 2.14M | 2.14M |
| Net income | -3.55M | -5.54M | -6.68M | -6.92M | -8.15M |
| Change in cash | -1.68M | 3.01M | -0.49M | 0.56M | -0.05M |
| Begin period cash flow | 3.11M | 0.10M | 0.59M | 0.05M | 0.11M |
| End period cash flow | 1.43M | 3.11M | 0.10M | 0.59M | 0.05M |
| Total cash from operating activities | -3.04M | -1.01M | -4.09M | -6.19M | -5.20M |
| Issuance of capital stock | 0.00M | 0.15M | - | - | - |
| Depreciation | 0.01M | 0.01M | 0.24M | 0.69M | 0.69M |
| Sale purchase of stock | - | - | 0.42M | 0.27M | 0.67M |
| Other cashflows from financing activities | - | 0.15M | 0.10M | 0.05M | 1.87M |
| Change to netincome | 0.06M | 0.04M | 0.13M | 0.02M | 0.08M |
| Capital expenditures | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Change receivables | - | - | 0.05M | 0.00M | 1.50M |
| Cash flows other operating | - | - | 0.34M | 0.09M | 0.03M |
| Cash and cash equivalents changes | - | - | -0.49M | 0.56M | -0.05M |
| Change in working capital | 0.45M | 4.47M | 2.14M | -0.05M | 2.18M |
| Stock based compensation | 0.00M | 0.02M | 0.13M | 0.02M | - |
| Other non cash items | 0.05M | 0.08M | 0.07M | 0.07M | 0.08M |
| Free cash flow | -3.04M | -1.01M | -4.09M | -6.19M | -5.20M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| PVCT Provectus Biopharmaceuticals Inc |
-0.00 8.65% |
0.05 | - | - | 67.35 | 5.44 | 151.25 | -15.14 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Provectus Biopharmaceuticals, Inc., a clinical-stage biotechnology company, engages in developing immunotherapy medicines based on halogenated xanthenes. The company's lead molecule is rose bengal sodium (RBS). Its clinical development programs include PV-10 for the treatment of stage III and IV melanoma and different types of liver cancers; PH-10 for the treatment of psoriasis and atopic dermatitis; and PV-305 for the treatment of infectious keratitis. The company is also developing oral formulations for adult solid tumor cancers, as well as refractory and relapsed pediatric, and other blood cancers comprising leukemias; PV-10 for the treatment of relapsed and refractory pediatric solid tumor cancers; and other formulations for the treatment of cutaneous canine cancers and healing of full-thickness cutaneous wounds. In addition, it develops oral and intranasal formulations for the treatment of severe acute respiratory syndrome coronavirus 2; gram-positive and gram-negative bacterial infections; oral bacterial infections; and fungal infections; as well as vertebrate development, wound healing, and tissue regrowth. The company has collaboration agreement with Bascom Palmer Eye Institute; and University of Miami. The company was formerly known as Provectus Pharmaceuticals, Inc. and changed its name to Provectus Biopharmaceuticals, Inc. in December 2013. Provectus Biopharmaceuticals, Inc. was founded in 2002 and is based in Knoxville, Tennessee.
10025 Investment Drive, Knoxville, TN, United States, 37932
866 594 5999
4
| Name | Title | Year Born |
|---|---|---|
| Dr. Eric A. Wachter | Co-Founder & CTO | 1963 |
| Ms. Heather Raines CPA | Chief Financial Officer | 1967 |
| Mr. Bruce Horowitz | COO & Director | 1956 |
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